|
1 / 1
|
DeCS
|
|
 |
|
Descriptor English:
|
|
DNA Gyrase
|
|
Descriptor Spanish:
|
|
ADN girasa
|
|
Descriptor Portuguese:
|
|
DNA Girase
|
|
Synonyms English:
|
|
DNA Gyrase A Subunit
DNA Gyrase B Subunit
DNA-Gyrase
GyrA Protein
GyrB Protein
|
|
Tree Number:
|
|
D08.811.399.403.741.149
D12.776.097.237
|
|
Definition English:
|
|
A bacterial DNA topoisomerase II that catalyzes ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. Gyrase binds to DNA as a heterotetramer consisting of two A and two B subunits. In the presence of ATP, gyrase is able to convert the relaxed circular DNA duplex into a superhelix. In the absence of ATP, supercoiled DNA is relaxed by DNA gyrase. |
|
Entry Combination - descr/qualif English:
|
|
DNA Gyrase/antagonists & inhibitors use Topoisomerase II Inhibitors
|
|
History Note English:
|
|
2002; use DNA TOPOISOMERASE (ATP-HYDROLYZING) 1994-2001, use DNA GYRASE 1980-1993; for GYRA PROTEIN use DNA TOPOISOMERASE (ATP-HYDROLYZING) (NM) 1992-2001; GYRB PROTEIN use DNA TOPOISOMERASE (ATP-HYDROLYZING) (NM) 1991-2001
|
|
Allowable Qualifiers English:
|
|
|
|
Record Number:
|
|
36089
|
|
Unique Identifier:
|
|
D027081
|
Occurrence in VHL:
|
|
|
Similar:
|
|
DeCS
|